ELDO™

The ELDO™ is a Vial to Syringe Transfer solution that helps reduce drug waste by maximizing the amount of drug extracted from a vial. It is customizable to various vial sizes, is easy to use and is shown to extract more drug from a vial than standard syringes alone. Congruence was selected as part of Blue Knight™ – a join initiative between Johnson & Johnson Innovation – JLABS and BARDA to advance this solution to minimize vaccine waste.

Configurations

Multi-Use per vial or Single-use per vial
Disposable (one per vial)

Key Benefits

Minimizes drug waste for low dose volumes
No additional steps compared to typical transfer device use

Availability

IP Protected
Samples available for clinical/preclinical use

Applications

Drugs and vaccines are commonly provided in vials. Since transfer from a vial to an injection system is required, some additional volume is filled in the vial to account for dead space in syringes and needles, and user inefficiencies – this additional volume is “overfill” and is typically wasted. In addition to increased cost, lost revenue, pharmaceutical waste also represents a sustainability issue.

In applications involving small volumes, the overfill can be significantly larger than the indicated dose volume, and the overfill problem is cumulative in multi-dose vials (e.g., vaccines).

ELDO™ technology helps utilize this overfill and prevent drug waste. ELDO™ can reduce waste and maximize number of doses for drugs in multi-dose vials or low injection volume from single-dose vials; these include vaccines, insulin, compounded medications, cell therapies, gene therapies and other expensive or scarce medications.

Data

Illustrated here is an example where ELDO™ approach is compared with conventional approach for vial to syringe transfer.

For a 2.2mL vial fill volume, seven (7) 0.3mL doses were extracted and dispensed with ELDO™ compared to five (5) 0.3mL doses with a conventional syringe and needle only.

~94% of the vial fill volume was drawn and injected with the ELDO™.

Additional data available upon request

Specifications


Key Needs Addressed	Microliter, Minimize Drug Waste
Device Type	Vial-Syringe Transfer System
User Profile	HCPs, Pharmacists, Self-administration
Administration Route	Subcutaneous, Intramuscular, Intravenous
Primary Container	Vial (Multiple Sizes)
Usage	Multi-Dose or Single-Dose; Disposable
Dosage Type	User-selected
Dose Volume	N/A
Viscosity	N/A
Injection Time	User Controlled
Priming & Dose Setting	Manual
Needle Attachment	N/A
Needle Safety	N/A
Injection Feedback	N/A

Instructions for use available upon request